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Biomolecular Machines
Proteins are true cellular nanomachines that perform sophisticated biological functions by self-assembling into dynamic 3D structures that use thermal energy to change shape in response to specific...
Macromolecular Assemblies and Hybrid Devices
The high rate of discovery in nanotechnology is permitting us to realize nanomaterials with interesting new properties that can be used for building hybrid devices in conjunction with biomolecules.
Cellular and Multicellular Systems
Differentiating Tissue: This sub-project is a targeted effort to understand, quantify, and direct cell-to-cell and mechanical signaling in differentiating stem cell populations.
Lab Experience for High School and Undergraduate Level Students
biophysics, bioengineering & biochemistry
Science & Technology Enrichment Program
creating an infrastructure that enables research opportunities for high school students

The NSF CREST Center for Cellular and Biomolecular Machines was established with a $5 million grant from the National Science Foundation and brings together more than a dozen faculty members from multiple units across campus, including bioengineering, physics, chemistry and chemical biology, materials science and engineering. Researchers are studying how biological matter like proteins or cells come together to perform specific tasks, in hopes of eventually being able to engineer and develop innovations ranging from designer cells and tissue to novel diagnostic and therapeutic devices. The CCBM also hosts an integrated, interdisciplinary training program for graduate students that emphasizes physical and biological components and research and training experiences for undergraduate and high school students to enhance the recruitment of underrepresented groups into STEM research.

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physics, bioengineering, materials science, quantitative biology, applied mathematics, chemistry and chemical biology forming a diverse, interdisciplinary research community with a common vision


nurturing teamwork, creativity, versatility and entrepreneurship for undergraduate and graduate students with a special emphasis on technical training 


K-12 programs focused on increasing the number and diversity of talented students in STEM fields & other special community-focused efforts

Featured News

July 11, 2019
On Friday, August 16, CCBM's Thrust 1 will host Dr. Lee-Ping Wang for a seminar titled, "Computational prediction of metamorphic proteins using secondary structure prediction uncertainty." Dr. Lee...
July 10, 2019
The CCBM is pleased to announce the Fall 2019 CCBM Fellows! Mark Bartolo (Sayantani Ghosh Lab) Melissa Goodlad (Tao Ye Lab) Alexander Li (Anand Subramaniam Lab) David Moses (Shahar Sukenik Lab...
Professor Strubbe stands in front of a research poster.
July 9, 2019

Durable, reliable, affordable solar power is the future of energy, and UC Merced computational physicist Professor David Strubbe is diving into a new area of science to answer the call. Strubbe’s...

July 2, 2019
As part of its mission to train the next generation of scientists, the CCBM will host three specialized training modules this summer - Computation...

Events and Happenings

Center for Cellular and Biomolecular Machines 3rd Annual CCBM Open House Friday, September 27, 2019 UC Merced, 5200 North Lake Road...
On Friday, August 23, 2019 the CCBM will host its Annual Retreat. 
On Friday, August 16, the NSF-CREST Center for Cellular and Biomolecular Machines will welcome UC Davis Professor Lee-Ping Wang to campus for a...
The Undergraduate Research Opportunities Center (UROC) will be hosting the 13th Annual Summer Research Symposium at UC Merced on Friday, August 2.